Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 4/20 | 0.55 |
| ▸ | WNT3A | P56704 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.43 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11166568 | 0.88 | SMN1; SMN2 (0.47) | CTNNB1WNT3ASMN1; SMN2HPGDTDP1 | |
| SCHEMBL3949461 | 0.88 | CTNNB1 (0.60) | CTNNB1WNT3ASMN1; SMN2HPGDTDP1 | |
| SCHEMBL1167294 | 0.86 | KMT2A (0.53) | CTNNB1WNT3ASMN1; SMN2HPGDTDP1 | |
| SCHEMBL11073319 | 0.85 | SMN1; SMN2 (0.50) | CTNNB1WNT3ASMN1; SMN2TDP1MAPT | |
| SCHEMBL4628989 | 0.84 | KMT2A (0.50) | CTNNB1WNT3ASMN1; SMN2HPGDTDP1 | |
| SCHEMBL2743418 | 0.82 | CTNNB1 (0.54) | CTNNB1WNT3AHPGDTDP1HDAC8 | |
| SCHEMBL12548319 | 0.82 | KMT2A (0.54) | CTNNB1WNT3AHPGDTDP1MAPT | |
| SCHEMBL30089541 | 0.81 | CTNNB1 (0.70) | CTNNB1WNT3ASMN1; SMN2HPGDTDP1 | |
| SCHEMBL29062364 | 0.81 | CTNNB1 (0.70) | CTNNB1WNT3ASMN1; SMN2HPGDTDP1 | |
| SCHEMBL22868041 | 0.80 | CTNNB1 (0.66) | CTNNB1WNT3ASMN1; SMN2HPGDHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4444981-A | ANTIINFLAMMATORY, ANALGESICS | BEECHAM GROUP LIMITED (GB) | 1984-04-24 | — | — | US | disclosed |
| EP-0024807-B1 | BENZOCYCLOHEPTAPYRROLEALKANOIC ACIDS AND THEIR DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1983-11-02 | — | — | EP | disclosed |
| EP-0024807-A1 | Benzocycloheptapyrrolealkanoic acids and their derivatives, processes for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1981-03-11 | — | — | EP | disclosed |