Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 14/20 | 0.63 |
| ▸ | HTR1A | P08908 | 12/20 | 0.63 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.55 |
| ▸ | HRH1 | P35367 | 3/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11068846 | 0.98 | SLC6A2 (0.61) | SLC6A2HTR1ASLC6A3SLC6A4HRH1 | |
| SCHEMBL20615067 | 0.83 | SLC6A2 (0.70) | SLC6A2HTR1ASLC6A3SLC6A4HRH1 | |
| SCHEMBL234010 | 0.83 | SLC6A2 (0.81) | SLC6A2HTR1ASLC6A3SLC6A4HRH1 | |
| SCHEMBL11066031 | 0.82 | HRH1 (0.53) | SLC6A2HTR1ASLC6A3SLC6A4HRH1 | |
| Hydrochloric Acid SCHEMBL3466964 | 0.81 | SLC6A2 (0.79) | SLC6A2HTR1ASLC6A3SLC6A4HRH1 | |
| SCHEMBL22278045 | 0.81 | SLC6A2 (0.63) | SLC6A2HTR1ASLC6A3SLC6A4HRH1 | |
| Hydrochloric Acid SCHEMBL11071373 | 0.81 | HRH1 (0.51) | SLC6A2HTR1ASLC6A3SLC6A4HRH1 | |
| SCHEMBL5473677 | 0.80 | HRH1 (0.58) | SLC6A2HTR1ASLC6A3SLC6A4HRH1 | |
| Hydrochloric Acid SCHEMBL22266112 | 0.79 | SLC6A2 (0.61) | SLC6A2HTR1ASLC6A3SLC6A4HRH1 | |
| SCHEMBL11063123 | 0.79 | SLC6A2 (0.61) | SLC6A2HTR1ASLC6A3SLC6A4HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443462-A | Antipsychotic 4-(naphthalenyloxy)piperidine derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1984-04-17 | — | — | US | disclosed |