Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 3/20 | 0.53 |
| ▸ | HTR2C | P28335 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 4/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.49 |
| ▸ | KHK | P50053 | 1/20 | 0.48 |
| ▸ | PNMT | P11086 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | JUND | P17535 | 1/20 | 0.43 |
| ▸ | FOSB | P53539 | 1/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11071373 | 0.98 | HRH1 (0.51) | HRH1HTR2CHTR1ASLC6A2SLC6A3 | |
| SCHEMBL1780546 | 0.84 | HRH1 (0.62) | HRH1HTR2CHTR1ASLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL4100905 | 0.83 | HRH1 (0.60) | HRH1HTR2CHTR1ASLC6A2SLC6A3 | |
| SCHEMBL11069093 | 0.82 | SLC6A2 (0.63) | HRH1HTR1ASLC6A2SLC6A3SLC6A4 | |
| Hydrochloric Acid SCHEMBL23360080 | 0.82 | HTR1A (0.46) | HRH1HTR2CHTR1ASLC6A2SLC6A3 | |
| SCHEMBL5473677 | 0.81 | HRH1 (0.58) | HRH1HTR1ASLC6A2SLC6A3KHK | |
| Hydrochloric Acid SCHEMBL11068846 | 0.81 | SLC6A2 (0.61) | HRH1HTR1ASLC6A2SLC6A3SLC6A4 | |
| Hydrochloric Acid SCHEMBL5460821 | 0.80 | HRH1 (0.57) | HRH1HTR1ASLC6A2SLC6A3KHK | |
| SCHEMBL27263702 | 0.78 | HRH1 (0.48) | HRH1HTR2CHTR1ASLC6A2SLC6A3 | |
| SCHEMBL11063098 | 0.78 | IKBKB (0.48) | HRH1HTR2CJUNDFOSBTLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443462-A | Antipsychotic 4-(naphthalenyloxy)piperidine derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1984-04-17 | — | — | US | disclosed |