Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26916403 | 0.85 | NOTUM (0.44) | NOTUMKMT2AMEN1SRD5A1ALDH1A1 | |
| SCHEMBL11147651 | 0.84 | NOTUM (0.66) | NOTUMTRIM24MAPTPOLBCYP2C9 | |
| SCHEMBL11147595 | 0.83 | NOTUM (0.47) | NOTUMTRIM24MAPTKMT2AMEN1 | |
| SCHEMBL11064543 | 0.83 | NOTUM (0.44) | NOTUMKDM4ETRIM24MAPTKMT2A | |
| SCHEMBL11064539 | 0.83 | NOTUM (0.44) | NOTUMKDM4ETRIM24MAPTKMT2A | |
| SCHEMBL11141196 | 0.82 | NOTUM (0.48) | NOTUMKMT2ASRD5A1LMNAHSD17B3 | |
| SCHEMBL5563636 | 0.81 | NOTUM (0.70) | NOTUMKDM4ETRIM24MAPTTHRB | |
| SCHEMBL9538397 | 0.81 | NOTUM (0.42) | NOTUMKDM4EMAPTKMT2AMEN1 | |
| SCHEMBL9535907 | 0.81 | NOTUM (0.47) | NOTUMMAPTTHRBTP53POLB | |
| SCHEMBL26405746 | 0.79 | BRD4 (0.46) | NOTUMKDM4EKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4440770-A | Diuretic, hypotensive and antiedemic quinoline oximes | MOCHIDA SEIYAKU KABUSHIKI KAISHA (JP) | 1984-04-03 | — | — | US | disclosed |
| US-4421919-A | ANTIEDEMIC, DIURETIC, HYPOTENSIVE | HODOGAYA CHEMICAL CO., LTD. (JP) | 1983-12-20 | — | — | US | disclosed |