Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | HCN1 | O60741 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28902453 | 0.82 | NR3C2 (0.52) | MAPTCRHBPCRHR2NPSR1NR3C2 | |
| SCHEMBL409370 | 0.79 | NR3C2 (0.57) | MAPTCRHBPCRHR2NPSR1NR3C2 | |
| SCHEMBL6567347 | 0.79 | NR3C2 (0.57) | MAPTCRHBPCRHR2NPSR1NR3C2 | |
| SCHEMBL7149333 | 0.77 | NR3C2 (0.60) | MAPTCRHBPCRHR2NPSR1NR3C2 | |
| Bromide SCHEMBL6737911 | 0.77 | NR3C2 (0.55) | MAPTCRHBPCRHR2NPSR1NR3C2 | |
| Iodide SCHEMBL31634397 | 0.77 | NR3C2 (0.55) | MAPTCRHBPCRHR2NPSR1NR3C2 | |
| Hydrochloric Acid SCHEMBL27464725 | 0.77 | NR3C2 (0.55) | MAPTCRHBPCRHR2NPSR1NR3C2 | |
| SCHEMBL11782372 | 0.76 | TSHR (0.38) | MAPTCRHBPCRHR2NPSR1NR3C2 | |
| SCHEMBL218046 | 0.75 | ALDH1A1 (0.42) | MAPTCRHBPCRHR2NPSR1TSHR | |
| SCHEMBL22681846 | 0.74 | NR3C2 (0.46) | MAPTCRHBPCRHR2NPSR1NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4452943-A | ADDING NITRILE-CONTAINING MATERIAL TO NON-POLAR THERMOPLASTIC POLYMER | GOLDMAN CONRAD | 1984-06-05 | — | — | US | disclosed |