Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.46 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.46 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HBB | P68871 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TK1 | P04183 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | PNP | P00491 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11079006 | 1.00 | ADRB1 (0.49) | ADRB1DNMT1PIM1CSNK2A2CSNK2B | |
| SCHEMBL13908934 | 1.00 | ADRB1 (0.49) | ADRB1DNMT1PIM1CSNK2A2CSNK2B | |
| SCHEMBL11069365 | 1.00 | ADRB1 (0.49) | ADRB1DNMT1PIM1CSNK2A2CSNK2B | |
| SCHEMBL5911880 | 0.89 | PIM1 (0.38) | ADRB1DNMT1PIM1CSNK2A2CSNK2B | |
| SCHEMBL5911886 | 0.89 | PIM1 (0.38) | ADRB1DNMT1PIM1CSNK2A2CSNK2B | |
| SCHEMBL5912553 | 0.89 | ADRB1 (0.38) | ADRB1DNMT1PIM1CSNK2A2CSNK2B | |
| SCHEMBL5911959 | 0.89 | ADRB1 (0.38) | ADRB1DNMT1PIM1CSNK2A2CSNK2B | |
| SCHEMBL5912562 | 0.89 | ADRB1 (0.38) | ADRB1DNMT1PIM1CSNK2A2CSNK2B | |
| SCHEMBL5911950 | 0.89 | ADRB1 (0.38) | ADRB1DNMT1PIM1CSNK2A2CSNK2B | |
| SCHEMBL5911916 | 0.86 | SLC29A1 (0.36) | ADRB1DNMT1PIM1CSNK2A2CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4462992-A | ANTITUMOR AND ANTICARCINOGENIC AGENTS | RESEARCH CORPORATION (US) | 1984-07-31 | — | — | US | disclosed |