Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | MMP1 | P03956 | 2/20 | 0.44 |
| ▸ | FCER2 | P06734 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 4/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15701675 | 0.82 | CYP19A1 (0.54) | CYP19A1PLAUHTR1ASIGMAR1GBA1 | |
| SCHEMBL1689627 | 0.82 | CYP19A1 (0.54) | CYP19A1PLAUHTR1ASIGMAR1GBA1 | |
| SCHEMBL6570371 | 0.82 | CYP19A1 (0.54) | CYP19A1PLAUHTR1ASIGMAR1GBA1 | |
| SCHEMBL19676939 | 0.81 | CYP19A1 (0.50) | CYP19A1PLAUHTR1ASIGMAR1MMP1 | |
| SCHEMBL6571517 | 0.79 | MMP1 (0.52) | CYP19A1HTR1ASIGMAR1MMP1FCER2 | |
| SCHEMBL6571514 | 0.79 | MMP1 (0.52) | CYP19A1HTR1ASIGMAR1MMP1FCER2 | |
| SCHEMBL6573689 | 0.79 | MMP1 (0.52) | CYP19A1HTR1ASIGMAR1MMP1FCER2 | |
| SCHEMBL7809851 | 0.79 | MMP1 (0.52) | CYP19A1HTR1ASIGMAR1MMP1FCER2 | |
| SCHEMBL16759785 | 0.79 | CYP19A1 (0.47) | CYP19A1PLAUHTR1ASIGMAR1MMP1 | |
| SCHEMBL6950638 | 0.77 | CYP19A1 (0.46) | CYP19A1PLAUHTR1ASIGMAR1MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4471052-A | Biosynthesis of simplified anthracyclines | ADRIA LABORATORIES, INC. (US) | 1984-09-11 | — | — | US | disclosed |