Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11069468 | 0.87 | GAA (0.47) | MAPTGAAALDH1A1NPC1KDM4E | |
| SCHEMBL10506561 | 0.87 | GAA (0.50) | CYP3A4MAPTGAAALDH1A1TSHR | |
| SCHEMBL10833802 | 0.84 | CYP3A4 (0.46) | CYP3A4MAPTALDH1A1TSHRHSD17B10 | |
| SCHEMBL10506227 | 0.84 | CYP3A4 (0.42) | CYP3A4MAPTGAAALDH1A1TSHR | |
| SCHEMBL10664581 | 0.83 | TSHR (0.45) | CYP3A4MAPTGAAALDH1A1TSHR | |
| SCHEMBL11074688 | 0.83 | MAPT (0.47) | MAPTGAAALDH1A1NPC1KDM4E | |
| SCHEMBL10665567 | 0.79 | CYP3A4 (0.43) | CYP3A4MAPTALDH1A1TSHRHSD17B10 | |
| SCHEMBL11076721 | 0.78 | KDM4E (0.57) | MAPTGAAALDH1A1NPC1KDM4E | |
| SCHEMBL8828541 | 0.75 | NPC1 (0.46) | MAPTGAAALDH1A1NPC1KDM4E | |
| SCHEMBL11184973 | 0.75 | ALDH1A1 (0.52) | MAPTALDH1A1TSHRNPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0023140-B1 | HERBICIDAL SULFONAMIDES, PREPARATION AND USE THEREOF, AND COMPOSITIONS CONTAINING THEM | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-10-31 | — | — | EP | claimed |
| EP-0023140-A2 | Herbicidal sulfonamides, preparation and use thereof, and compositions containing them | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-01-28 | — | — | EP | claimed |
| EP-0023140-B1 | HERBICIDAL SULFONAMIDES, PREPARATION AND USE THEREOF, AND COMPOSITIONS CONTAINING THEM | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-10-31 | — | — | EP | disclosed |
| US-4342587-A | Herbicidal pyridinsulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-08-03 | — | — | US | disclosed |
| EP-0023140-A2 | Herbicidal sulfonamides, preparation and use thereof, and compositions containing them | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-01-28 | — | — | EP | disclosed |