Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | TTR | P02766 | 1/20 | 0.57 |
| ▸ | ALB | P02768 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.49 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10883530 | 0.87 | TDP1 (0.71) | TDP1MEN1TTRALBTHRB | |
| SCHEMBL11048022 | 0.84 | TDP1 (0.51) | TDP1MEN1TTRALBTHRB | |
| SCHEMBL11076466 | 0.84 | TDP1 (0.51) | TDP1MEN1TTRALBTHRB | |
| SCHEMBL2326248 | 0.83 | MAPT (0.64) | TDP1MEN1TTRALBTHRB | |
| SCHEMBL11076939 | 0.82 | MEN1 (0.56) | TDP1MEN1TTRALBTHRB | |
| SCHEMBL11649655 | 0.80 | HSPB1 (0.50) | TDP1MEN1TTRALBTHRB | |
| SCHEMBL11042108 | 0.80 | TDP1 (0.51) | TDP1MEN1TTRALBTHRB | |
| SCHEMBL7406297 | 0.78 | MAPT (0.59) | TDP1MEN1TTRALBTHRB | |
| SCHEMBL11432939 | 0.78 | RHEB (0.53) | TDP1MEN1KMT2AMAPTPOLB | |
| SCHEMBL11734899 | 0.78 | MEN1 (0.48) | TDP1MEN1TTRALBTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0027555-B1 | PROCESS FOR THE PREPARATION OF DIPHENYL ETHERS | CELAMERCK GmbH & Co. KG (DE) | 1984-01-04 | — | — | EP | disclosed |
| US-4364875-A | AMINATION, ISOMER-FREE END-PRODUCTS | CELAMERCK GMBH & CO. KG (DE) | 1982-12-21 | — | — | US | disclosed |
| EP-0027555-A1 | Process for the preparation of diphenyl ethers | CELAMERCK GmbH & Co. KG (DE) | 1981-04-29 | — | — | EP | disclosed |