Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Uracil SCHEMBL28248900 | 0.76 | — | — | |
| Uracil SCHEMBL11607890 | 0.74 | — | — | |
| Uracil SCHEMBL8235 | 0.74 | — | — | |
| Uracil SCHEMBL5089507 | 0.74 | — | — | |
| Uracil SCHEMBL3798527 | 0.74 | CRBN (1.00) | CRBNMMP2TP53 | |
| Uracil SCHEMBL151239 | 0.74 | — | — | |
| Uracil SCHEMBL28426792 | 0.72 | CRBN (0.85) | CRBNMMP2TP53PDE3BPDE3A | |
| Uracil SCHEMBL11130705 | 0.72 | — | — | |
| Uracil SCHEMBL18010636 | 0.72 | — | — | |
| Uracil SCHEMBL156275 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4431646-A | TRANQUILIZERS; PSYCHOSIS; NERVOUS SYSTEM DISORDERS | PFIZER INC. (US) | 1984-02-14 | — | — | US | disclosed |
| EP-0060610-A1 | Hexahydro-trans- and tetrahydropyridoindole neuroleptic agents | PFIZER INC. (US) | 1982-09-22 | — | — | EP | disclosed |
| EP-0028316-A1 | Process for the preparation of 2,4-diaminopyrimidine | HÜLS TROISDORF AKTIENGESELLSCHAFT (DE) | 1981-05-13 | — | — | EP | disclosed |
| US-4150228-A | PHOTOGRAPHIC COMPLEXING AGENTS | POLAROID CORPORATION (US) | 1979-04-17 | — | — | US | disclosed |