Uracil

Uracil

SCHEMBL3798527

O=c1cc[nH]c(=O)[nH]1.O=c1cc[nH]c(=O)[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 3/20 1.00
MMP2 P08253 1/20 0.59
TP53 P04637 1/20 0.56
TYMP P19971 1/20 0.39
GSK3B P49841 1/20 0.39
BACE1 P56817 1/20 0.39
FKBP5 Q13451 1/20 0.38
CA1 P00915 2/20 0.35
CCR8 P51685 1/20 0.35
NOTUM Q6P988 1/20 0.34
ALDH1A1 P00352 3/20 0.33
AOC3 Q16853 1/20 0.33
DPYD Q12882 1/20 0.33
KMT2A Q03164 1/20 0.33
GAA P10253 1/20 0.33
IDO1 P14902 1/20 0.33
ATAD2 Q6PL18 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
CYP19A1 P11511 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Uracil SCHEMBL5089507 1.00
Uracil SCHEMBL8235 1.00
Uracil SCHEMBL11607890 1.00
Uracil SCHEMBL11130705 0.97
Uracil SCHEMBL156275 0.97
Uracil SCHEMBL18010636 0.97
Uracil SCHEMBL3165194 0.97
Uracil SCHEMBL21385227 0.97
Uracil SCHEMBL710130 0.97
Uracil SCHEMBL228901 0.97

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114106125-B Ginkgo peptide, special medical formula food containing ginkgo peptide and application of ginkgo peptide 大连海洋大学 2023-08-08 CN disclosed
CN-114106125-A Ginkgo peptide, special medical formula food containing same and application thereof 大连海洋大学 2022-03-01 CN disclosed
CN-111778362-A Novel freeze-dried nucleic acid detection kit and detection method for coronavirus, influenza virus and pneumonia virus 深圳容金科技有限公司 2020-10-16 CN disclosed
CN-108079982-B Modified silica gel filler, preparation method and application 苏州纳微科技股份有限公司 2020-03-13 CN disclosed
CN-110290794-A The microRNA and its purposes in cancer treatment of 5- halo uracil modification 纽约州州立大学研究基金会 2019-09-27 CN disclosed
CN-110195037-A A kind of human umblilical vein endothelial primary separation and culture method 西安交通大学 2019-09-03 CN disclosed
US-20190214145-A1 Method and systems for creating and screening patient metabolite profile to diagnose current medical condition, diagnose current treatment state and recommend new treatment regimen KUREK ITZHAK (US) 2019-07-11 US disclosed
CN-109827985-A It is a kind of based on NMR metabolism group to the discrimination method of maca different cultivars 长春中医药大学 2019-05-31 CN disclosed
CN-109390037-A The full site recognition methods of mature miRNA based on SVM-AdaBoost 齐齐哈尔大学 2019-02-26 CN disclosed
EP-3390324-A1 FERTILIZER COMPOSITIONS FOR PLANTS AND SOILS Envirokure Incorporated (US) 2018-10-24 EP disclosed
CN-101496774-A Cosmetic composition comprising ascorbic acid 2-glucoside and ergothioneine LVMH RECH (FR) 2009-08-05 CN disclosed
US-7557175-B2 Poly(carbonate-co-urea) copolymers and melt transesterification method of preparing these copolymers SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-07-07 US disclosed
US-20090142285-A1 COSMETIC COMPOSITION COMPRISING ASCORBIC ACID 2-GLUCOSIDE AND ERGOTHIONEINE LVMH RECHERCHE 2009-06-04 US disclosed
US-20080233164-A1 Polymer for Use in Conduits, Medical Devices and Biomedical Surface Modification UCL BIOMEDICAL PLC (GB) 2008-09-25 US disclosed
CN-1324034-C Dioxazole pyrimidine nucleotide compounds with function of releasing NO and its use in pharmaceutics CHINESE PHARMACEUTICAL UNIV (CN) 2007-07-04 CN disclosed
EP-0491793-B1 2'-DEOXY-4'-THIORIBONUCLEOSIDES AS ANTIVIRAL AND ANTICANCER AGENTS SOUTHERN RES INST (US) 2005-11-30 EP disclosed
CN-1583753-A Dioxazole pyrimidine nucleotide compounds with function of releasing NO and its use in pharmaceutics CHINESE PHARMACEUTICAL UNIV (CN) 2005-02-23 CN disclosed
US-5591722-A ANTICANCER AGENTS SOUTHERN RESEARCH INSTITUTE (US) 1997-01-07 US disclosed
EP-0491793-A4 2'-DEOXY-4'-THIORIBONUCLEOSIDES AS ANTIVIRAL AND ANTICANCER AGENTS 1993-03-03 EP disclosed
EP-0491793-A1 2'-DEOXY-4'-THIORIBONUCLEOSIDES AS ANTIVIRAL AND ANTICANCER AGENTS SOUTHERN RESEARCH INSTITUTE (US) 1992-07-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090142285-A1 COSMETIC COMPOSITION COMPRISING ASCORBIC ACID 2-GLUCOSIDE AND ERGOTHIONEINE OGG1, MPG, UNG CRBN 4352/4885MMP2 707/4885TP53 1396/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.