Uracil

Uracil

SCHEMBL3798527

O=c1cc[nH]c(=O)[nH]1.O=c1cc[nH]c(=O)[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 3/20 1.00
▸ MMP2 P08253 1/20 0.59
▸ TP53 P04637 1/20 0.56
▸ TYMP P19971 1/20 0.39
▸ GSK3B P49841 1/20 0.39
▸ BACE1 P56817 1/20 0.39
▸ FKBP5 Q13451 1/20 0.38
▸ CA1 P00915 2/20 0.35
▸ CCR8 P51685 1/20 0.35
▸ NOTUM Q6P988 1/20 0.34
▸ ALDH1A1 P00352 3/20 0.33
▸ AOC3 Q16853 1/20 0.33
▸ DPYD Q12882 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ GAA P10253 1/20 0.33
▸ IDO1 P14902 1/20 0.33
▸ ATAD2 Q6PL18 1/20 0.33
▸ LMNA P02545 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ CYP19A1 P11511 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Uracil SCHEMBL8235 1.00 — —
Uracil SCHEMBL11607890 1.00 — —
Uracil SCHEMBL5089507 1.00 — —
Uracil SCHEMBL710130 0.97 — —
Uracil SCHEMBL2161716 0.97 — —
Uracil SCHEMBL18010636 0.97 — —
Uracil SCHEMBL16116311 0.97 — —
Uracil SCHEMBL4664232 0.97 CRBN (0.94) CRBNMMP2TP53TYMPGSK3B
Uracil SCHEMBL21385227 0.97 — —
Uracil SCHEMBL8767625 0.97 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114106125-B Ginkgo peptide, special medical formula food containing ginkgo peptide and application of ginkgo peptide 大连海洋大学 2023-08-08 — — CN disclosed
CN-114106125-A Ginkgo peptide, special medical formula food containing same and application thereof 大连海洋大学 2022-03-01 — — CN disclosed
CN-111778362-A Novel freeze-dried nucleic acid detection kit and detection method for coronavirus, influenza virus and pneumonia virus 深圳容金科技有限公司 2020-10-16 — — CN disclosed
CN-108079982-B Modified silica gel filler, preparation method and application 苏州纳微科技股份有限公司 2020-03-13 — — CN disclosed
CN-110290794-A The microRNA and its purposes in cancer treatment of 5- halo uracil modification 纽约州州立大学研究基金会 2019-09-27 — — CN disclosed
CN-110195037-A A kind of human umblilical vein endothelial primary separation and culture method 西安交通大学 2019-09-03 — — CN disclosed
US-20190214145-A1 Method and systems for creating and screening patient metabolite profile to diagnose current medical condition, diagnose current treatment state and recommend new treatment regimen KUREK ITZHAK (US) 2019-07-11 — — US disclosed
CN-109827985-A It is a kind of based on NMR metabolism group to the discrimination method of maca different cultivars 长春中医药大学 2019-05-31 — — CN disclosed
CN-109390037-A The full site recognition methods of mature miRNA based on SVM-AdaBoost 齐齐哈尔大学 2019-02-26 — — CN disclosed
EP-3390324-A1 FERTILIZER COMPOSITIONS FOR PLANTS AND SOILS Envirokure Incorporated (US) 2018-10-24 — — EP disclosed
CN-101496774-A Cosmetic composition comprising ascorbic acid 2-glucoside and ergothioneine LVMH RECH (FR) 2009-08-05 — — CN disclosed
US-7557175-B2 Poly(carbonate-co-urea) copolymers and melt transesterification method of preparing these copolymers SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-07-07 — — US disclosed
US-20090142285-A1 COSMETIC COMPOSITION COMPRISING ASCORBIC ACID 2-GLUCOSIDE AND ERGOTHIONEINE LVMH RECHERCHE 2009-06-04 — — US disclosed
US-20080233164-A1 Polymer for Use in Conduits, Medical Devices and Biomedical Surface Modification UCL BIOMEDICAL PLC (GB) 2008-09-25 — — US disclosed
CN-1324034-C Dioxazole pyrimidine nucleotide compounds with function of releasing NO and its use in pharmaceutics CHINESE PHARMACEUTICAL UNIV (CN) 2007-07-04 — — CN disclosed
EP-0491793-B1 2'-DEOXY-4'-THIORIBONUCLEOSIDES AS ANTIVIRAL AND ANTICANCER AGENTS SOUTHERN RES INST (US) 2005-11-30 — — EP disclosed
CN-1583753-A Dioxazole pyrimidine nucleotide compounds with function of releasing NO and its use in pharmaceutics CHINESE PHARMACEUTICAL UNIV (CN) 2005-02-23 — — CN disclosed
US-5591722-A ANTICANCER AGENTS SOUTHERN RESEARCH INSTITUTE (US) 1997-01-07 — — US disclosed
EP-0491793-A4 2'-DEOXY-4'-THIORIBONUCLEOSIDES AS ANTIVIRAL AND ANTICANCER AGENTS — 1993-03-03 — — EP disclosed
EP-0491793-A1 2'-DEOXY-4'-THIORIBONUCLEOSIDES AS ANTIVIRAL AND ANTICANCER AGENTS SOUTHERN RESEARCH INSTITUTE (US) 1992-07-01 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090142285-A1 COSMETIC COMPOSITION COMPRISING ASCORBIC ACID 2-GLUCOSIDE AND ERGOTHIONEINE OGG1, MPG, UNG CRBN 4352/4885MMP2 707/4885TP53 1396/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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