Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11067449 | 0.86 | HTT (0.63) | HTTBRD4HPGDALDH1A1MEN1 | |
| SCHEMBL11063781 | 0.85 | HTT (0.53) | HTTKCNK3KCNK9KMT2ARAB9A | |
| SCHEMBL11064168 | 0.82 | HTT (0.59) | HTTBRD4HPGDALDH1A1MEN1 | |
| SCHEMBL11067159 | 0.80 | HTT (0.59) | HTTBRD4HPGDALDH1A1MEN1 | |
| SCHEMBL11071246 | 0.79 | HTT (0.58) | HTTBRD4HPGDALDH1A1MEN1 | |
| SCHEMBL11061106 | 0.78 | HTT (0.56) | HTTHPGDALDH1A1KCNK3KCNK9 | |
| SCHEMBL11071119 | 0.78 | HTT (0.50) | HTTHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL11058483 | 0.77 | HTT (0.55) | HTTHPGDALDH1A1KCNK9MEN1 | |
| SCHEMBL11058478 | 0.77 | HTT (0.55) | HTTHPGDALDH1A1KCNK9MEN1 | |
| SCHEMBL11060964 | 0.77 | HTT (0.55) | HTTHPGDALDH1A1KCNK9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435394-A | 3-Sulfonamido-benzophenonimine derivatives useful for treating virus infections | SHIONOGI & CO., LTD. (JP) | 1984-03-06 | — | — | US | claimed |
| US-4435394-A | 3-Sulfonamido-benzophenonimine derivatives useful for treating virus infections | SHIONOGI & CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |