Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PDXK | O00764 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11744174 | 0.90 | KDM4E (0.54) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL11743153 | 0.90 | KDM4E (0.54) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL30583160 | 0.83 | SGPL1 (0.53) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL4321398 | 0.83 | SGPL1 (0.53) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL6282607 | 0.81 | KDM4E (0.55) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL20214836 | 0.80 | KDM4E (0.65) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| Pyridoxine SCHEMBL5364587 | 0.76 | KDM4E (0.73) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL3786515 | 0.76 | HPGD (0.58) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL18556353 | 0.76 | KDM4E (0.58) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL9684755 | 0.75 | GAA (0.51) | ALDH1A1KDM4EHPGDHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0053347-B1 | RADIOACTIVE DIAGNOSTIC AGENT AND NON-RADIOACTIVE CARRIER THEREFOR | NIHON MEDI-PHYSICS CO., LTD. (JP) | 1984-10-17 | — | — | EP | disclosed |
| US-4440739-A | TECHNETIUM, N-PYRIDOXYL-A-AMINO ACID | NIHON MEDI-PHYSICS CO., LTD. (JP) | 1984-04-03 | — | — | US | disclosed |
| EP-0053347-A2 | Radioactive diagnostic agent and non-radioactive carrier therefor | NIHON MEDI-PHYSICS CO., LTD. (JP) | 1982-06-09 | — | — | EP | disclosed |