Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PDXK | O00764 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20214836 | 0.85 | KDM4E (0.65) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL7242817 | 0.79 | KDM4E (0.73) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL3786515 | 0.78 | HPGD (0.58) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL11743153 | 0.77 | KDM4E (0.54) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL11744174 | 0.77 | KDM4E (0.54) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL18617699 | 0.77 | KDM4E (0.71) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL15586891 | 0.77 | KDM4E (0.71) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL7193519 | 0.77 | KDM4E (0.56) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL6271143 | 0.76 | KDM4E (0.69) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL31010835 | 0.76 | KDM4E (0.69) | KDM4EALDH1A1HPGDHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9580383-B2 | Compositions and methods for the treatment of multiple sclerosis | CELLIX BIO PRIVATE LIMITED (IN) | 2017-02-28 | — | — | US | disclosed |