Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 15/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 14/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylbenzene SCHEMBL11069651 | 0.81 | OPRL1 (0.47) | OPRL1OPRM1TACR1SLC6A4KDM1A | |
| SCHEMBL11071916 | 0.81 | OPRM1 (0.38) | OPRL1OPRM1 | |
| SCHEMBL11069827 | 0.79 | GRIN2B (0.42) | OPRL1OPRM1 | |
| Ethylbenzene SCHEMBL11066834 | 0.77 | OPRL1 (0.51) | OPRL1OPRM1TACR1SLC6A4KDM1A | |
| SCHEMBL11071936 | 0.76 | SLC6A4 (0.39) | OPRL1OPRM1SLC6A4 | |
| Ethylbenzene SCHEMBL11065452 | 0.76 | OPRM1 (0.55) | OPRL1OPRM1 | |
| Ethylbenzene SCHEMBL11073164 | 0.75 | OPRM1 (0.52) | OPRL1OPRM1TACR1SLC6A4MEN1 | |
| Ethylbenzene SCHEMBL11078303 | 0.74 | OPRM1 (0.57) | OPRL1OPRM1 | |
| SCHEMBL11072284 | 0.72 | PARP1 (0.33) | — | |
| Ethylbenzene SCHEMBL11070027 | 0.72 | OPRM1 (0.51) | OPRL1OPRM1TACR1SLC6A4KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |