Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.46 |
| ▸ | F2 | P00734 | 2/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.46 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.46 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 3/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11075874 | 1.00 | RARB (0.51) | RARBMAPK1PRSS1F2PRSS2 | |
| SCHEMBL6139653 | 1.00 | RARB (0.51) | RARBMAPK1PRSS1F2PRSS2 | |
| SCHEMBL11350271 | 0.98 | RARB (0.50) | RARBMAPK1PRSS1F2PRSS2 | |
| SCHEMBL11249595 | 0.88 | PRSS1 (0.44) | RARBPRSS1F2PRSS2PRSS3 | |
| SCHEMBL11234832 | 0.88 | PRSS1 (0.44) | RARBPRSS1F2PRSS2PRSS3 | |
| SCHEMBL11563318 | 0.85 | PRSS1 (0.42) | RARBMAPK1PRSS1F2PRSS2 | |
| SCHEMBL11562499 | 0.85 | POLB (0.57) | MAPK1PRSS1F2PRSS2PRSS3 | |
| SCHEMBL11286580 | 0.85 | PRSS1 (0.44) | RARBMAPK1PRSS1F2PRSS2 | |
| Hydrochloric Acid SCHEMBL11070829 | 0.85 | PRSS1 (0.46) | RARBMAPK1PRSS1F2PRSS2 | |
| SCHEMBL11350229 | 0.85 | PRSS1 (0.44) | MAPK1PRSS1F2PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4485105-A | Method of treating hyperlipidemia with 4-(monoalkylamino)benzoic acid amides | AMERICAN CYANAMID COMPANY (US) | 1984-11-27 | — | — | US | disclosed |
| US-4242273-A | ANTILIPEMIC AND ANTICHOLESTEROL AGENTS | AMERICAN CYANAMID COMPANY (US) | 1980-12-30 | — | — | US | disclosed |
| US-4154756-A | HYPOLIPIDEMIC AND ANTIATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1979-05-15 | — | — | US | disclosed |
| US-4136256-A | HYPOLIPIDEMIC, ANTIATHEROSCLEROTIC | AMERICAN CYANAMID COMPANY (US) | 1979-01-23 | — | — | US | disclosed |