Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.58 |
| ▸ | NPC1 | O15118 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27147314 | 0.83 | RAB9A (0.63) | RAB9ANPC1ALDH1A1GAAMEN1 | |
| SCHEMBL1706695 | 0.80 | RAB9A (0.53) | RAB9ANPC1ALDH1A1GAAMEN1 | |
| SCHEMBL8956172 | 0.80 | RAB9A (0.60) | RAB9ANPC1ALDH1A1GAAMEN1 | |
| SCHEMBL30893646 | 0.80 | RAB9A (0.60) | RAB9ANPC1ALDH1A1GAAMEN1 | |
| SCHEMBL23092268 | 0.80 | RAB9A (0.60) | RAB9ANPC1ALDH1A1GAAMEN1 | |
| Hydrochloric Acid SCHEMBL27152067 | 0.79 | RAB9A (0.62) | RAB9ANPC1ALDH1A1GAAMEN1 | |
| SCHEMBL11325966 | 0.76 | RAB9A (0.56) | RAB9ANPC1ALDH1A1GAAMEN1 | |
| SCHEMBL7876698 | 0.76 | RAB9A (0.56) | RAB9ANPC1ALDH1A1GAAMEN1 | |
| SCHEMBL12066273 | 0.75 | PDE10A (0.66) | RAB9ANPC1ALDH1A1GAAMEN1 | |
| SCHEMBL24332825 | 0.74 | RAB9A (1.00) | RAB9ANPC1ALDH1A1GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4529722-A | A 7-ureidoacetamido-7a-methoxy-3-(1-(2-hydroxyethyl)-1H-tetrazol-5 -yl)thiomethyl-1-dethia-1-oxa-3-cephem carboxylic acid derivative | SHIONOGI & CO., LTD. (JP) | 1985-07-16 | — | — | US | disclosed |
| EP-0034249-B1 | NEW NAPHTHIMIDAZOLE AND NAPHTHOXAZOLE DERIVATIVES, THEIR PREPARATION, AND THEIR USE IN PHARMACEUTICALS | GRUPPO LEPETIT S.P.A. (IT) | 1984-10-24 | — | — | EP | disclosed |
| US-4461894-A | Naphth[1,2-d]imidazoles | GRUPPO LEPETIT S.P.A. (IT) | 1984-07-24 | — | — | US | disclosed |
| US-4360674-A | Naphth[1,2-d]imidazoles | GRUPPO LEPETIT S.P.A. (IT) | 1982-11-23 | — | — | US | disclosed |
| EP-0034249-A2 | New naphthimidazole and naphthoxazole derivatives, their preparation, and their use in pharmaceuticals | GRUPPO LEPETIT S.P.A. (IT) | 1981-08-26 | — | — | EP | disclosed |