Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.44 |
| ▸ | RARB | P10826 | 3/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | RARG | P13631 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11485420 | 0.94 | TSHR (0.47) | PPARATSHRCASP1SMN1; SMN2PPARG | |
| SCHEMBL10898569 | 0.88 | KAT8 (0.48) | PPARAPPARGKAT8RARBRARA | |
| SCHEMBL22032180 | 0.88 | TSHR (0.50) | PPARATSHRCASP1SMN1; SMN2PPARG | |
| SCHEMBL5539478 | 0.81 | IGF1R (0.54) | IGF1RALOX15CDK1MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL27670238 | 0.81 | PPARA (0.68) | PPARAPPARGKAT8RARBRARA | |
| SCHEMBL11120604 | 0.81 | KAT8 (0.68) | PPARACASP1PPARGKAT8IGF1R | |
| SCHEMBL5545868 | 0.79 | IGF1R (0.56) | IGF1RALOX15MEN1KMT2APYGL | |
| SCHEMBL22032157 | 0.77 | TSHR (0.49) | PPARATSHRCASP1SMN1; SMN2NR1H4 | |
| SCHEMBL9952446 | 0.76 | TSHR (0.55) | PPARATSHRCASP1SMN1; SMN2NR1H4 | |
| SCHEMBL27605961 | 0.76 | TSHR (0.55) | PPARATSHRCASP1SMN1; SMN2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126372-A1 | Halogenated protease inhibitors | G.D. Searle & Co. (US) | 1984-11-28 | — | — | EP | claimed |