Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 17/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 14/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylbenzene SCHEMBL11073164 | 0.91 | OPRM1 (0.52) | OPRM1OPRL1OPRD1OPRK1TACR1 | |
| Ethylbenzene SCHEMBL11073743 | 0.91 | OPRM1 (0.42) | OPRM1OPRL1OPRD1OPRK1TACR1 | |
| Ethylbenzene SCHEMBL11074468 | 0.90 | OPRM1 (0.41) | OPRM1OPRL1OPRD1OPRK1SLC6A4 | |
| Ethylbenzene SCHEMBL11074460 | 0.86 | OPRM1 (0.43) | OPRM1OPRL1OPRD1OPRK1TACR1 | |
| SCHEMBL11070088 | 0.84 | OPRM1 (0.48) | OPRM1OPRL1OPRD1OPRK1SLC6A4 | |
| SCHEMBL11070091 | 0.81 | OPRM1 (0.50) | OPRM1OPRL1OPRD1OPRK1SLC6A4 | |
| Ethylbenzene SCHEMBL11068803 | 0.77 | OPRM1 (0.39) | OPRM1OPRD1OPRK1TACR1SLC6A4 | |
| SCHEMBL11069986 | 0.77 | OPRM1 (0.48) | OPRM1OPRL1OPRD1OPRK1 | |
| Ethylbenzene SCHEMBL11070027 | 0.77 | OPRM1 (0.51) | OPRM1OPRL1TACR1SLC6A4 | |
| SCHEMBL11076240 | 0.76 | OPRM1 (0.44) | OPRM1OPRL1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |