Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 11/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11073989 | 0.96 | ABCB11 (0.47) | ABCB11LMNAMAPTMAPK1EPHX1 | |
| SCHEMBL11022703 | 0.95 | ABCB11 (0.43) | ABCB11LMNAMAPTMAPK1EPHX1 | |
| SCHEMBL11073550 | 0.91 | ABCB11 (0.53) | ABCB11LMNAMAPTMAPK1EPHX1 | |
| SCHEMBL11075284 | 0.90 | ABCB11 (0.39) | ABCB11LMNAMAPTMAPK1EPHX1 | |
| SCHEMBL11021372 | 0.90 | ABCB11 (0.50) | ABCB11LMNAMAPTMAPK1EPHX1 | |
| SCHEMBL11080379 | 0.90 | ABCB11 (0.50) | ABCB11LMNAMAPTMAPK1EPHX1 | |
| SCHEMBL11075276 | 0.90 | ABCB11 (0.50) | ABCB11LMNAMAPTMAPK1EPHX1 | |
| SCHEMBL11073851 | 0.90 | ABCB11 (0.50) | ABCB11LMNAMAPTMAPK1EPHX1 | |
| SCHEMBL11077144 | 0.89 | ABCB11 (0.50) | ABCB11LMNAMAPTMAPK1EPHX1 | |
| SCHEMBL11071660 | 0.89 | ABCB11 (0.50) | ABCB11LMNAMAPTMAPK1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0042307-B1 | AN OPTICAL RECORDING ELEMENT AND A METHOD OF RECORDING INFORMATION USING THE ELEMENT | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1986-09-10 | — | — | EP | disclosed |
| US-4430339-A | PROPHYLAXIS, METABOLISM, GLUCOSE, FATS, HYPOGLYCEMIC AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-02-07 | — | — | US | disclosed |
| WO-1982000822-A1 | SUBSTITUTED OXIRANECARBOXYLIC ACIDS,THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | EISTETTER K | 1982-03-18 | — | — | WO | disclosed |