Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 3/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071877 | 0.99 | TP53 (0.39) | TP53NAAAMAPTEPHX1KDM5A | |
| SCHEMBL11068957 | 0.99 | TP53 (0.39) | TP53NAAAMAPTEPHX1KDM5A | |
| SCHEMBL11081734 | 0.99 | TP53 (0.39) | TP53NAAAMAPTEPHX1KDM5A | |
| SCHEMBL11079199 | 0.99 | TP53 (0.38) | TP53NAAAMAPTEPHX1CTSK | |
| SCHEMBL11081590 | 0.97 | NAAA (0.39) | TP53NAAAMAPTEPHX1CTSK | |
| SCHEMBL11069012 | 0.94 | TP53 (0.44) | TP53NAAAMAPTKDM5APHF8 | |
| SCHEMBL11072363 | 0.94 | MAPT (0.40) | TP53NAAAMAPTEPHX1CTSK | |
| SCHEMBL11074086 | 0.93 | MAPT (0.40) | NAAAMAPTEPHX1CTSKCPB2 | |
| SCHEMBL11073505 | 0.93 | MAPT (0.40) | NAAAMAPTEPHX1CTSKCPB2 | |
| SCHEMBL11074011 | 0.93 | MAPT (0.40) | NAAAMAPTEPHX1CTSKCPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4430339-A | PROPHYLAXIS, METABOLISM, GLUCOSE, FATS, HYPOGLYCEMIC AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-02-07 | — | — | US | disclosed |
| WO-1982000822-A1 | SUBSTITUTED OXIRANECARBOXYLIC ACIDS,THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | EISTETTER K | 1982-03-18 | — | — | WO | disclosed |