Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 11/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 10/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11076435 | 0.85 | OPRM1 (0.42) | OPRL1OPRM1SLC6A4SLC6A3 | |
| SCHEMBL4348575 | 0.84 | OPRL1 (0.59) | OPRL1OPRM1SLC6A4SLC6A3ATM | |
| SCHEMBL11078781 | 0.82 | OPRL1 (0.43) | OPRL1OPRM1 | |
| SCHEMBL11071653 | 0.79 | MAPK1 (0.40) | OPRL1OPRM1SLC6A4SLC6A3L3MBTL1 | |
| SCHEMBL11073735 | 0.74 | OPRL1 (0.38) | OPRL1OPRM1SLC6A4SLC6A3 | |
| Ethylbenzene SCHEMBL11078303 | 0.73 | OPRM1 (0.57) | OPRL1OPRM1 | |
| SCHEMBL11070143 | 0.72 | OPRL1 (0.56) | OPRL1OPRM1SLC6A4SLC6A3MAOB | |
| SCHEMBL11076076 | 0.72 | MDM2 (0.42) | OPRL1OPRM1SLC6A4SLC6A3 | |
| SCHEMBL11070312 | 0.72 | OPRM1 (0.44) | OPRL1OPRM1SLC6A4 | |
| SCHEMBL3407329 | 0.72 | OPRM1 (1.00) | OPRL1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |