SCHEMBL11070204

SCHEMBL11070204

CCc1cc(OC)ccc1C(=O)OC

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.54
CYP1A2 P05177 1/20 0.54
CYP2D6 P10635 1/20 0.54
CYP2C9 P11712 1/20 0.54
CYP2C19 P33261 1/20 0.54
NR4A2 P43354 1/20 0.50
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
CA1 P00915 3/20 0.48
CA2 P00918 3/20 0.48
HSD17B10 Q99714 2/20 0.47
ALDH1A1 P00352 3/20 0.47
HPGD P15428 3/20 0.47
CYP3A4 P08684 1/20 0.47
MAPK1 P28482 1/20 0.47
GAA P10253 2/20 0.46
GLA P06280 1/20 0.46
TAS1R3 Q7RTX0 1/20 0.46
TAS1R1 Q7RTX1 1/20 0.46
MAPT P10636 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7921525 0.88 KDM4E (0.57) KDM4ECYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL7849332 0.86 KDM4E (0.51) KDM4ECYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL8385229 0.86 KDM4E (0.51) KDM4ECYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL4551259 0.86 HPGD (0.57) KDM4ENPC1RAB9ACA1CA2
SCHEMBL896633 0.86 KDM4E (0.51) KDM4ECYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL13469244 0.86 KDM4E (0.58) KDM4ECYP1A2CYP2D6CYP2C9CYP2C19
Hydrochloric Acid SCHEMBL6382403 0.85 CYP1A2 (0.44) KDM4ECYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL3089078 0.85 ALDH1A1 (0.47) NPC1RAB9AHSD17B10ALDH1A1HPGD
SCHEMBL21464329 0.85 KDM4E (0.51) KDM4ECYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL5730634 0.84 ALDH1A1 (0.62) KDM4ECYP1A2CYP2C19NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4444567-A ALKOXY BENZALDEHYDES, ALKOXY BENZOATES PHILLIPS PETROLEUM COMPANY (US) 1984-04-24 US disclosed