Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | HTR1D | P28221 | 1/20 | 0.51 |
| ▸ | HTR1B | P28222 | 1/20 | 0.51 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GCGR | P47871 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11074701 | 0.94 | MEN1 (0.53) | MEN1KMT2APOLBALOX5HTR1D | |
| SCHEMBL11077438 | 0.93 | MEN1 (0.53) | MEN1KMT2APOLBALOX5HTR1D | |
| SCHEMBL11074981 | 0.92 | MEN1 (0.52) | MEN1KMT2APOLBALOX5HTR1D | |
| SCHEMBL11074885 | 0.90 | MEN1 (0.56) | MEN1KMT2APOLBALOX5HTR1D | |
| SCHEMBL11072103 | 0.89 | MEN1 (0.60) | MEN1KMT2APOLBALOX5MGAM | |
| SCHEMBL11074728 | 0.88 | MEN1 (0.50) | MEN1KMT2APOLBALOX5MAPT | |
| Trifenagrel SCHEMBL31058836 | 0.88 | MEN1 (0.63) | MEN1KMT2APOLBALOX5MGAM | |
| Trifenagrel SCHEMBL4428157 | 0.88 | MEN1 (0.63) | MEN1KMT2APOLBALOX5MGAM | |
| Trifenagrel SCHEMBL11078277 | 0.86 | MEN1 (0.62) | MEN1KMT2APOLBALOX5MGAM | |
| SCHEMBL11077260 | 0.86 | MEN1 (0.54) | MEN1KMT2APOLBALOX5MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0058890-B1 | ANTITHROMBOTIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-09-26 | — | — | EP | claimed |
| EP-0058890-A1 | Antithrombotic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1982-09-01 | — | — | EP | claimed |
| EP-0058890-B1 | ANTITHROMBOTIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-09-26 | — | — | EP | disclosed |
| EP-0029171-B1 | AZOLYLOXY-CARBOXYLIC ACID N-OXY-AMIDES, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION, THEIR USE, HERBICIDES CONTAINING THEM AND THEIR PREPARATION | BAYER AG (DE) | 1984-03-21 | — | — | EP | disclosed |
| EP-0081730-A1 | Process for the preparation of hetaryloxyacetamides | BAYER AG (DE) | 1983-06-22 | — | — | EP | disclosed |
| EP-0029183-B1 | TETRAZOLYLOXYCARBON AMIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | BAYER AG (DE) | 1983-01-12 | — | — | EP | disclosed |
| EP-0058890-A1 | Antithrombotic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1982-09-01 | — | — | EP | disclosed |
| EP-0048850-A1 | 1-Benzotriazolyloxy-acetic-acid amides, process for their preparation and their use as herbicides | BAYER AG (DE) | 1982-04-07 | — | — | EP | disclosed |
| EP-0029183-A1 | Tetrazolyloxycarbon amides, process for their preparation and their use as herbicides | BAYER AG (DE) | 1981-05-27 | — | — | EP | disclosed |