Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | GCGR | P47871 | 2/20 | 0.41 |
| ▸ | PDE5A | O76074 | 2/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11077260 | 0.93 | MEN1 (0.54) | MEN1KMT2APOLBMGAMKDM4E | |
| SCHEMBL11070403 | 0.89 | MEN1 (0.57) | MEN1KMT2APOLBMGAMKDM4E | |
| SCHEMBL11080279 | 0.87 | MEN1 (0.61) | MEN1KMT2APOLBMGAMKDM4E | |
| Trifenagrel SCHEMBL31058836 | 0.85 | MEN1 (0.63) | MEN1KMT2APOLBMGAMKDM4E | |
| Trifenagrel SCHEMBL4428157 | 0.85 | MEN1 (0.63) | MEN1KMT2APOLBMGAMKDM4E | |
| SCHEMBL14646372 | 0.84 | MEN1 (0.72) | MEN1KMT2APOLBMGAMKDM4E | |
| Trifenagrel SCHEMBL11078277 | 0.84 | MEN1 (0.62) | MEN1KMT2APOLBMGAMKDM4E | |
| SCHEMBL11074885 | 0.84 | MEN1 (0.56) | MEN1KMT2APOLBMGAMKDM4E | |
| SCHEMBL11074701 | 0.83 | MEN1 (0.53) | MEN1KMT2APOLBMGAMKDM4E | |
| SCHEMBL11077438 | 0.82 | MEN1 (0.53) | MEN1KMT2APOLBMGAMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0058890-B1 | ANTITHROMBOTIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-09-26 | — | — | EP | claimed |
| EP-0058890-B1 | ANTITHROMBOTIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-09-26 | — | — | EP | disclosed |