Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | PTGIR | P43119 | 1/20 | 0.35 |
| ▸ | PRLHR | P49683 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10836067 | 0.80 | HSD17B10 (0.50) | CYP3A4LMNANR1I2CYP1A2CYP2D6 | |
| SCHEMBL11470919 | 0.78 | HSD17B10 (0.57) | CYP3A4LMNANR1I2CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL11469730 | 0.77 | HSD17B10 (0.60) | CYP3A4LMNANR1I2CYP1A2CYP2D6 | |
| SCHEMBL11193303 | 0.76 | HSD17B10 (0.45) | CYP3A4LMNANR1I2CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL11191037 | 0.75 | HSD17B10 (0.47) | CYP3A4LMNANR1I2CYP1A2CYP2D6 | |
| SCHEMBL11187623 | 0.74 | HSD17B10 (0.41) | CYP3A4LMNANR1I2CYP1A2CYP2D6 | |
| SCHEMBL11187463 | 0.74 | HSD17B10 (0.39) | CYP3A4LMNANR1I2CYP1A2CYP2D6 | |
| SCHEMBL11185140 | 0.74 | HSD17B10 (0.39) | CYP3A4LMNANR1I2CYP1A2CYP2D6 | |
| SCHEMBL11067664 | 0.72 | CYP3A4 (0.47) | CYP3A4LMNANR1I2CYP1A2CYP2D6 | |
| SCHEMBL11185552 | 0.70 | HPGD (0.38) | TSHRHSD17B10ALDH1A1MEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4425351-A | ANTIANOXIC | SYNTHELABO (FR) | 1984-01-10 | — | — | US | claimed |