Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | PTGIR | P43119 | 1/20 | 0.37 |
| ▸ | PRLHR | P49683 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10995066 | 0.81 | HTR1A (0.50) | CYP3A4TSHRNR1I2LMNACYP1A2 | |
| Hydrochloric Acid SCHEMBL11485625 | 0.81 | HTR1A (0.49) | CYP3A4TSHRNR1I2LMNACYP1A2 | |
| SCHEMBL11187131 | 0.78 | HTR1A (0.40) | CYP3A4TSHRNR1I2LMNACYP1A2 | |
| SCHEMBL11183362 | 0.78 | MAPT (0.38) | CYP3A4TSHRNR1I2LMNACYP1A2 | |
| SCHEMBL11190369 | 0.77 | AKR1B10 (0.43) | CYP3A4TSHRNR1I2LMNACYP1A2 | |
| SCHEMBL11183034 | 0.77 | AKR1B10 (0.39) | CYP3A4TSHRNR1I2LMNACYP1A2 | |
| SCHEMBL11186857 | 0.73 | AKR1B10 (0.39) | CYP3A4TSHRNR1I2LMNACYP1A2 | |
| SCHEMBL11180471 | 0.73 | MEN1 (0.40) | CYP3A4TSHRNR1I2LMNACYP1A2 | |
| SCHEMBL11190408 | 0.73 | CYP3A4 (0.38) | CYP3A4TSHRNR1I2LMNACYP1A2 | |
| SCHEMBL11188710 | 0.72 | AKR1B10 (0.41) | CYP3A4TSHRNR1I2LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4425351-A | ANTIANOXIC | SYNTHELABO (FR) | 1984-01-10 | — | — | US | claimed |
| US-4425351-A | ANTIANOXIC | SYNTHELABO (FR) | 1984-01-10 | — | — | US | disclosed |