Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 9/20 | 0.66 |
| ▸ | ATP4B | P51164 | 9/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11004320 | 0.81 | ATP4A (0.43) | ATP4AATP4BMEN1KMT2ACYP1A2 | |
| SCHEMBL2191092 | 0.80 | ATP4A (1.00) | ATP4AATP4BMEN1KMT2ACYP1A2 | |
| SCHEMBL11112221 | 0.78 | ATP4A (0.45) | ATP4AATP4BMEN1KMT2ACYP1A2 | |
| SCHEMBL2193550 | 0.77 | ATP4A (0.73) | ATP4AATP4BMEN1KMT2ACYP1A2 | |
| SCHEMBL10917761 | 0.77 | ATP4A (0.67) | ATP4AATP4BMEN1KMT2ACYP1A2 | |
| SCHEMBL2192235 | 0.75 | ATP4A (0.64) | ATP4AATP4BMEN1KMT2ACYP1A2 | |
| SCHEMBL2191115 | 0.75 | ATP4A (1.00) | ATP4AATP4BMEN1KMT2ACYP1A2 | |
| SCHEMBL8131625 | 0.75 | ATP4A (0.60) | ATP4AATP4BCYP3A4CYP2C9MAPK1 | |
| SCHEMBL11275143 | 0.72 | ATP4A (0.59) | ATP4AATP4BMEN1KMT2AMAPK1 | |
| SCHEMBL10920093 | 0.71 | ATP4A (0.69) | ATP4AATP4BMEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4450164-A | ANTIULCER AND ANTISECRETORY AGENTS | SCHERING CORPORATION (US) | 1984-05-22 | — | — | US | claimed |