Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1609142 | 0.84 | MAPT (0.61) | MAPTPKMCYP1A2ALDH1A1GAA | |
| SCHEMBL1608919 | 0.83 | SMN1; SMN2 (0.61) | MAPTPKMCYP1A2ALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL11271192 | 0.83 | MAPT (0.59) | MAPTPKMCYP1A2ALDH1A1GAA | |
| SCHEMBL10917670 | 0.80 | CYP1A2 (0.64) | MAPTPKMCYP1A2ALDH1A1GAA | |
| SCHEMBL11270696 | 0.80 | MAPT (0.53) | MAPTPKMCYP1A2ALDH1A1GAA | |
| SCHEMBL10919482 | 0.80 | MAPT (0.53) | MAPTPKMCYP1A2ALDH1A1GAA | |
| SCHEMBL10918194 | 0.80 | MAPT (0.48) | MAPTPKMCYP1A2ALDH1A1MEN1 | |
| SCHEMBL38664509 | 0.79 | PKM (0.54) | MAPTPKMCYP1A2ALDH1A1GAA | |
| SCHEMBL10733909 | 0.79 | MAPT (0.60) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL27574855 | 0.79 | SMN1; SMN2 (0.57) | MAPTPKMCYP1A2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4469868-A | ANTIPSYCHOTIC ANGENTS | WARNER-LAMBERT COMPANY (US) | 1984-09-04 | — | — | US | disclosed |
| EP-0095289-A2 | Imidazo(1,2-c)pyrazolo(3,4-e)pyrimidines and their production | WARNER-LAMBERT COMPANY (US) | 1983-11-30 | — | — | EP | disclosed |
| US-4317823-A | FOR TREATMENT OF GASTROINTESTINAL DISORDERS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-03-02 | — | — | US | disclosed |
| US-3939161-A | ANTIINFLAMMATORY, ANTISECRETORY | ABBOTT LABORATORIES (US) | 1976-02-17 | — | — | US | disclosed |