Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 6/20 | 0.55 |
| ▸ | ATP4B | P51164 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.38 |
| ▸ | PREP | P48147 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2193505 | 0.95 | ATP4A (0.60) | ATP4AATP4BMEN1CYP1A2CYP3A4 | |
| SCHEMBL2193356 | 0.78 | ATP4A (0.60) | ATP4AATP4BMEN1CYP1A2CYP3A4 | |
| SCHEMBL2195615 | 0.78 | ATP4A (0.47) | ATP4AATP4BMEN1CYP1A2CYP3A4 | |
| SCHEMBL2189812 | 0.77 | ATP4A (0.86) | ATP4AATP4BMEN1CYP1A2CYP3A4 | |
| SCHEMBL10920612 | 0.76 | ATP4A (0.62) | ATP4AATP4BMEN1CYP1A2CYP3A4 | |
| SCHEMBL2198369 | 0.72 | ATP4A (0.55) | ATP4AATP4BMEN1CYP2D6KMT2A | |
| SCHEMBL2191435 | 0.71 | ATP4A (0.77) | ATP4AATP4BMEN1CYP1A2CYP3A4 | |
| SCHEMBL2191115 | 0.71 | ATP4A (1.00) | ATP4AATP4BMEN1CYP1A2CYP3A4 | |
| SCHEMBL13098219 | 0.69 | HTR2A (0.54) | MAPK1KMT2AHDAC6 | |
| SCHEMBL10960061 | 0.68 | ATP4A (0.49) | ATP4AATP4BMEN1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4450164-A | ANTIULCER AND ANTISECRETORY AGENTS | SCHERING CORPORATION (US) | 1984-05-22 | — | — | US | disclosed |