Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 12/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11070748 | 1.00 | SPHK1 (0.42) | SPHK1CYP2C9MAPTALDH1A1LMNA | |
| SCHEMBL11076135 | 0.98 | CYP2C9 (0.42) | SPHK1CYP2C9MAPTALDH1A1LMNA | |
| SCHEMBL11076133 | 0.98 | CYP2C9 (0.42) | SPHK1CYP2C9MAPTALDH1A1LMNA | |
| SCHEMBL11076011 | 0.94 | SPHK1 (0.42) | SPHK1MAPTMEN1KMT2ASPHK2 | |
| SCHEMBL11073342 | 0.94 | SPHK1 (0.42) | SPHK1MAPTMEN1KMT2ASPHK2 | |
| SCHEMBL11076013 | 0.94 | SPHK1 (0.42) | SPHK1MAPTMEN1KMT2ASPHK2 | |
| SCHEMBL11073344 | 0.94 | SPHK1 (0.42) | SPHK1MAPTMEN1KMT2ASPHK2 | |
| SCHEMBL11075966 | 0.94 | CYP2C9 (0.43) | SPHK1CYP2C9MAPTALDH1A1LMNA | |
| SCHEMBL11075962 | 0.94 | CYP2C9 (0.43) | SPHK1CYP2C9MAPTALDH1A1LMNA | |
| SCHEMBL11069790 | 0.92 | MEN1 (0.42) | SPHK1CYP2C9MAPTMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4462923-A | Disubstituted pyrimidines | HOFFMANN-LA ROCHE INC. (US) | 1984-07-31 | — | — | US | disclosed |