Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 5/20 | 0.39 |
| ▸ | HMGCR | P04035 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11066474 | 1.00 | PTPN7 (0.39) | PTPN7HMGCRKMT2ASMN1; SMN2RECQL | |
| SCHEMBL11064022 | 0.98 | PTPN7 (0.37) | PTPN7HMGCRKMT2ASMN1; SMN2RECQL | |
| SCHEMBL11065426 | 0.94 | KMT2A (0.33) | PTPN7HMGCRKMT2ASMN1; SMN2SPHK1 | |
| SCHEMBL11064727 | 0.92 | FAAH (0.43) | PTPN7HMGCRKMT2ARECQLTDP1 | |
| SCHEMBL11063371 | 0.92 | FAAH (0.43) | PTPN7HMGCRKMT2ARECQLTDP1 | |
| SCHEMBL11070761 | 0.92 | FAAH (0.43) | PTPN7HMGCRKMT2ARECQLTDP1 | |
| SCHEMBL11064725 | 0.92 | FAAH (0.43) | PTPN7HMGCRKMT2ARECQLTDP1 | |
| SCHEMBL11064315 | 0.92 | FAAH (0.43) | PTPN7HMGCRKMT2ARECQLTDP1 | |
| SCHEMBL11063515 | 0.90 | FAAH (0.43) | PTPN7HMGCRKMT2ARECQLTDP1 | |
| SCHEMBL11068321 | 0.89 | FAAH (0.49) | PTPN7KMT2ARECQLTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4456619-A | Amides of 2-alkynoic acids and use for inhibiting accumulation of cholesterol ester in arterial walls | SANDOZ, INC. (US) | 1984-06-26 | — | — | US | disclosed |