Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MLYCD | O95822 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 4/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11545983 | 0.82 | PLK1 (0.45) | PLK1L3MBTL1MLYCDSCN5AABCB11 | |
| SCHEMBL11074814 | 0.80 | PLK1 (0.53) | PLK1L3MBTL1MLYCDNAAASCN5A | |
| SCHEMBL11067061 | 0.80 | L3MBTL1 (0.51) | PLK1L3MBTL1MLYCDNAAASCN5A | |
| SCHEMBL11071683 | 0.78 | PLK1 (0.56) | PLK1L3MBTL1MLYCDNAAASCN5A | |
| SCHEMBL11065504 | 0.77 | PLK1 (0.51) | PLK1L3MBTL1MLYCDNAAASCN5A | |
| SCHEMBL11280317 | 0.75 | PLK1 (0.50) | PLK1L3MBTL1SCN5AABCB11CYP3A4 | |
| SCHEMBL11277879 | 0.75 | PLK1 (0.50) | PLK1L3MBTL1SCN5AABCB11CYP3A4 | |
| SCHEMBL10993382 | 0.75 | PLK1 (0.50) | PLK1L3MBTL1SCN5AABCB11CYP3A4 | |
| SCHEMBL11273393 | 0.75 | PLK1 (0.50) | PLK1L3MBTL1SCN5AABCB11CYP3A4 | |
| SCHEMBL11287744 | 0.75 | PLK1 (0.50) | PLK1L3MBTL1SCN5AABCB11CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4485105-A | Method of treating hyperlipidemia with 4-(monoalkylamino)benzoic acid amides | AMERICAN CYANAMID COMPANY (US) | 1984-11-27 | — | — | US | disclosed |
| US-4242273-A | ANTILIPEMIC AND ANTICHOLESTEROL AGENTS | AMERICAN CYANAMID COMPANY (US) | 1980-12-30 | — | — | US | disclosed |
| US-4136256-A | HYPOLIPIDEMIC, ANTIATHEROSCLEROTIC | AMERICAN CYANAMID COMPANY (US) | 1979-01-23 | — | — | US | disclosed |