Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 6/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.33 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071088 | 1.00 | PTGIR (0.33) | PTGIRTSHRPTGER4PTGER2HPGD | |
| SCHEMBL11038783 | 0.93 | PTGIR (0.34) | PTGIRTSHRPTGER4PTGER2HPGD | |
| SCHEMBL11038780 | 0.93 | PTGIR (0.34) | PTGIRTSHRPTGER4PTGER2HPGD | |
| SCHEMBL10963649 | 0.80 | PTGIR (0.37) | PTGIRTSHRPTGER4PTGER2HPGD | |
| SCHEMBL10963646 | 0.80 | PTGIR (0.37) | PTGIRTSHRPTGER4PTGER2HPGD | |
| SCHEMBL10964037 | 0.80 | PTGIR (0.37) | PTGIRTSHRPTGER4PTGER2HPGD | |
| SCHEMBL10964047 | 0.80 | PTGIR (0.37) | PTGIRTSHRPTGER4PTGER2HPGD | |
| SCHEMBL11067100 | 0.79 | ALDH1A1 (0.34) | — | |
| SCHEMBL10965451 | 0.79 | PTGIR (0.38) | PTGIRTSHRPTGER4PTGER2HPGD | |
| SCHEMBL10965448 | 0.79 | PTGIR (0.38) | PTGIRTSHRPTGER4PTGER2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4466980-A | Thiaprostaglandin E1 derivatives, process for production thereof, and pharmaceutical use thereof | TEIJIN LIMITED (JP) | 1984-08-21 | — | — | US | disclosed |