Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.31 |
| ▸ | LSS | P48449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11066836 | 0.90 | KCNN4 (0.31) | KCNN4 | |
| SCHEMBL11068775 | 0.87 | OPRL1 (0.36) | OPRM1KCNN4LSS | |
| SCHEMBL11066676 | 0.85 | — | — | |
| SCHEMBL11070118 | 0.83 | OPRM1 (0.37) | OPRM1LSS | |
| SCHEMBL11070165 | 0.81 | OPRM1 (0.34) | OPRM1LSS | |
| SCHEMBL11077826 | 0.81 | OPRM1 (0.36) | OPRM1LSS | |
| SCHEMBL11080087 | 0.79 | OPRM1 (0.31) | OPRM1 | |
| SCHEMBL11073838 | 0.78 | KCNN4 (0.32) | KCNN4 | |
| SCHEMBL11073833 | 0.77 | KCNN4 (0.32) | KCNN4 | |
| SCHEMBL11078350 | 0.77 | OPRM1 (0.37) | OPRM1LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |