Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TOP1 | P11387 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8215023 | 1.00 | LMNA (0.69) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL9614379 | 1.00 | LMNA (0.69) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL11079234 | 1.00 | LMNA (0.69) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL11075814 | 1.00 | LMNA (0.69) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL11451770 | 1.00 | LMNA (0.69) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL3801509 | 1.00 | LMNA (0.69) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL11221597 | 0.97 | TDP1 (0.71) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL11218387 | 0.97 | TDP1 (0.71) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Mannitol SCHEMBL23066399 | 0.83 | LMNA (1.00) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Mannitol SCHEMBL2297640 | 0.83 | LMNA (1.00) | LMNAL3MBTL1TDP1KDM4EPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4442123-A | 6-Chloro-6-deoxy-D-hexitols, compositions containing them and their use in fertility control | TATE & LYLE PUBLIC LIMITED COMPANY (GB) | 1984-04-10 | — | — | US | claimed |
| EP-0015652-B1 | 6-CHLORO-6-DEOXY-D-HEXITOLS, THEIR ESTERS, THEIR PREPARATION, FERTILITY CONTROL COMPOSITIONS CONTAINING THEM AND THEIR USE IN A CONTRACEPTIVE METHOD | TATE & LYLE PUBLIC LIMITED COMPANY (GB) | 1983-01-19 | — | — | EP | claimed |
| EP-0015652-A1 | 6-Chloro-6-deoxy-D-hexitols, their esters, their preparation, fertility control compositions containing them and their use in a contraceptive method | TATE & LYLE PUBLIC LIMITED COMPANY (GB) | 1980-09-17 | — | — | EP | claimed |
| US-20180180626-A1 | A METHOD FOR DEVELOPMENT OF RECOMBINANT PROTEINS WITH FINGERPRINT LIKE SIMILARITY TO THE REFERENCE PRODUCT | STC BIOLOGICS INC (US) | 2018-06-28 | — | — | US | disclosed |
| US-9868973-B2 | Method for optimizing post-translational modifications on recombinant proteins | STC BIOLOGICS, INC. (US) | 2018-01-16 | — | — | US | disclosed |
| US-20160340706-A1 | Method for Optimizing Post-Translational Modifications on Recombinant Proteins | STC BIOLOGICS, INC. | 2016-11-24 | — | — | US | disclosed |
| EP-3094639-A1 | METHOD FOR OPTIMIZING POST-TRANSLATIONAL MODIFICATIONS ON RECOMBINANT PROTEINS | Leszcyniecka, Magdalena (US) | 2016-11-23 | — | — | EP | disclosed |
| WO-2015106276-A1 | METHOD FOR OPTIMIZING POST-TRANSLATIONAL MODIFICATIONS ON RECOMBINANT PROTEINS | LESZCYNIECKA MAGDALENA (US) | 2015-07-16 | — | — | WO | disclosed |
| US-4442123-A | 6-Chloro-6-deoxy-D-hexitols, compositions containing them and their use in fertility control | TATE & LYLE PUBLIC LIMITED COMPANY (GB) | 1984-04-10 | — | — | US | disclosed |
| EP-0015652-B1 | 6-CHLORO-6-DEOXY-D-HEXITOLS, THEIR ESTERS, THEIR PREPARATION, FERTILITY CONTROL COMPOSITIONS CONTAINING THEM AND THEIR USE IN A CONTRACEPTIVE METHOD | TATE & LYLE PUBLIC LIMITED COMPANY (GB) | 1983-01-19 | — | — | EP | disclosed |
| EP-0015652-A1 | 6-Chloro-6-deoxy-D-hexitols, their esters, their preparation, fertility control compositions containing them and their use in a contraceptive method | TATE & LYLE PUBLIC LIMITED COMPANY (GB) | 1980-09-17 | — | — | EP | disclosed |