Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 5/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071569 | 0.86 | PDE3B (0.47) | PDE3BPDE3AALDH1A1KDM4E | |
| SCHEMBL11061198 | 0.86 | MEN1 (0.38) | POLB | |
| SCHEMBL11067558 | 0.81 | KMT2A (0.36) | PDE3BPDE3AALDH1A1 | |
| SCHEMBL11067714 | 0.80 | PYGL (0.38) | ALDH1A1 | |
| SCHEMBL11064304 | 0.79 | PDE3B (0.46) | PDE3BPDE3AALDH1A1 | |
| SCHEMBL11062550 | 0.78 | PDE3B (0.40) | PDE3BPDE3A | |
| SCHEMBL11064332 | 0.78 | PDE3B (0.38) | PDE3BPDE3AALDH1A1KDM4E | |
| SCHEMBL11058595 | 0.74 | PDE3B (0.35) | PDE3BPDE3AALDH1A1 | |
| SCHEMBL11066234 | 0.73 | PDE3B (0.68) | PDE3BPDE3ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11067577 | 0.72 | PDE3B (0.38) | PDE3BPDE3AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435404-A | ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |