Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.45 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.45 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | ALB | P02768 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 1/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.45 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1437577 | 0.97 | CHRM1 (0.47) | CHRM1PDE4APTGS1PTGS2LMNA | |
| Ammonia Solution, Strong SCHEMBL27822658 | 0.95 | CHRM1 (0.46) | CHRM1PDE4APTGS1PTGS2LMNA | |
| Methoxymethane SCHEMBL27754240 | 0.91 | CXCR1 (0.43) | CHRM1PDE4APTGS1PTGS2LMNA | |
| Cyanide SCHEMBL28128025 | 0.91 | PYCR1 (0.43) | CHRM1PDE4APTGS1PTGS2LMNA | |
| SCHEMBL25014403 | 0.91 | MEN1 (0.46) | CHRM1PDE4APTGS1PTGS2LMNA | |
| SCHEMBL23696953 | 0.91 | MEN1 (0.46) | CHRM1PDE4APTGS1PTGS2LMNA | |
| SCHEMBL1169949 | 0.85 | PYCR1 (0.40) | CHRM1PDE4APTGS1PTGS2LMNA | |
| SCHEMBL3437767 | 0.85 | NPC1 (0.45) | CHRM1PDE4APTGS1PTGS2LMNA | |
| SCHEMBL13719134 | 0.85 | MAPT (0.47) | CHRM1PDE4APTGS1PTGS2LMNA | |
| SCHEMBL9375073 | 0.85 | PTGS1 (0.52) | CHRM1PDE4APTGS1PTGS2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0074008-B1 | PROCESS FOR PRODUCING ALPHA-ARYLALKANOIC ACID ESTERS | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1984-10-10 | — | — | EP | disclosed |
| US-4433160-A | Process for producing α-arylalkanoic acid ester | TAISHO PHARMACEUTICAL COMPANY, LTD. (JP) | 1984-02-21 | — | — | US | disclosed |
| EP-0074008-A2 | Process for producing alpha-arylalkanoic acid esters | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1983-03-16 | — | — | EP | disclosed |