Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 20/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1107162 | 0.93 | CCR3 (0.78) | CCR3 | |
| SCHEMBL1098034 | 0.88 | CCR3 (1.00) | CCR3 | |
| SCHEMBL2565773 | 0.85 | CCR3 (1.00) | CCR3 | |
| SCHEMBL2564463 | 0.83 | CCR3 (1.00) | CCR3 | |
| SCHEMBL1107153 | 0.82 | CCR3 (0.85) | CCR3 | |
| SCHEMBL1107155 | 0.79 | CCR3 (0.78) | CCR3 | |
| SCHEMBL4000148 | 0.78 | CCR3 (1.00) | CCR3 | |
| SCHEMBL1107157 | 0.78 | CCR3 (1.00) | CCR3 | |
| SCHEMBL1107154 | 0.78 | CCR3 (0.71) | CCR3 | |
| SCHEMBL2143252 | 0.77 | CCR3 (1.00) | CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153660-B2 | Piperidyl-propane-thiol CCR3 modulators | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-04-10 | — | — | US | disclosed |
| US-8153660-B2 | Piperidyl-propane-thiol CCR3 modulators | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-04-10 | — | — | US | disclosed |
| EP-2079725-B1 | PIPERIDYL-PROPANE-THIOL CCR3 MODULATORS | BOEHRINGER INGELHEIM INT (DE) | 2011-12-14 | — | — | EP | disclosed |
| US-20100317634-A1 | PIPERIDYL-PROPANE-THIOL CCR3 MODULATORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-12-16 | — | — | US | disclosed |
| US-20100317634-A1 | PIPERIDYL-PROPANE-THIOL CCR3 MODULATORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-12-16 | — | — | US | disclosed |
| WO-2008049874-A1 | PIPERIDYL-PROPANE-THIOL CCR3 MODULATORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-05-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317634-A1 | PIPERIDYL-PROPANE-THIOL CCR3 MODULATORS | CCR3, CCR1, CCRL2 | CCR3 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.