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CCRL2

C-C chemokine receptor-like 2 · O00421 · CCRL2 on Sugi Atlas →

3,519 patent compounds predicted against CCRL2, 1,960 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL9998107 SCHEMBL9998107 1.00 20/20
SCHEMBL9998176 SCHEMBL9998176 1.00 20/20
SCHEMBL9998450 SCHEMBL9998450 1.00 20/20
SCHEMBL9998458 SCHEMBL9998458 1.00 20/20
SCHEMBL9998544 SCHEMBL9998544 1.00 20/20
SCHEMBL9998545 SCHEMBL9998545 1.00 20/20
SCHEMBL9998569 SCHEMBL9998569 1.00 20/20
SCHEMBL9998610 SCHEMBL9998610 1.00 20/20
SCHEMBL9998612 SCHEMBL9998612 1.00 20/20
SCHEMBL9998701 SCHEMBL9998701 1.00 20/20
SCHEMBL9998703 SCHEMBL9998703 1.00 20/20
SCHEMBL9998943 SCHEMBL9998943 1.00 20/20
SCHEMBL9998944 SCHEMBL9998944 1.00 20/20
SCHEMBL9998945 SCHEMBL9998945 1.00 20/20
SCHEMBL9998946 SCHEMBL9998946 1.00 20/20
SCHEMBL9998948 SCHEMBL9998948 1.00 20/20
SCHEMBL9998949 SCHEMBL9998949 1.00 20/20
SCHEMBL9998957 SCHEMBL9998957 1.00 20/20
SCHEMBL9998958 SCHEMBL9998958 1.00 20/20
SCHEMBL9998968 SCHEMBL9998968 1.00 20/20

Clinical trials — most relevant to CCRL2 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Leronlimab in Patients With Coronavirus Disease 2019 (COVID-19) With Need for Mechanical Ventilation or Extracorporeal Membrane Oxygenation PHASE3SUSPENDED
Leronlimab in Moderately Ill Patients With COVID-19 Pneumonia PHASE3SUSPENDED
Assessment the Activity Value of Isotretinoin (13- Cis-Retinoic Acid ) in the Treatment of COVID-19 ( Isotretinoin in Treatment of COVID-19) (Randomized) PHASE3UNKNOWN
Intensive Locoregional Chemoimmunotherapy, Intradermal Autologous Alpha-DC1 Vaccines, and Systemic Pembrolizumab for Advanced-Stage Ovarian Cancer PHASE2NOT_YET_RECRUITING
Safety Study of a Chemokine Receptor (CXCR4) Antagonist in Multiple Myeloma Patients PHASE1/PHASE2COMPLETED
Biomarker Study of PDR001 in Combination With MCS110 in Gastric Cancer PHASE2UNKNOWN
Aerosol Combination Therapy of All-trans Retinoic Acid and Isotretinoin as A Novel Treatment for Inducing Neutralizing Antibodies in COVID -19 Infected Patients Better Than Vaccine : An Innovative Treatment PHASE2UNKNOWN
A Phase I Trial Anti-CC Chemokine Receptor 4 Chimeric Antigen Receptor T Cells (CCR4 CAR T Cells) for CCR4 Expressing T-cell Malignancies Including Peripheral T-cell Non-Hodgkin Lymphoma (PTCL) and Cutaneous T-cell Non-Hodgkin Lymphoma (CTCL) PHASE1RECRUITING
Placebo-controlled Assessment of the Effect of a Food Supplement on Skin Protection After Exposure to UV Radiation PHASE1COMPLETED
U69-CART-Cells For R/R T-ALL PHASE1RECRUITING
Circular RNA and Chemerin in Breast Cancer Patient nanUNKNOWN
Genetic Polymorphism Associated With Coronary Heart Disease Susceptibility and Variability of Clopidogrel Response nanACTIVE_NOT_RECRUITING
Inflammatory Biomarkers in Psychogenic Non-epileptic Seizure nanUNKNOWN
Evaluation of CCR6 Gene Expression and Circulating CCL20 Levels as Potential Biomarkers in Rheumatoid Arthritis nanNOT_YET_RECRUITING
C-X-C Chemokine Receptor 4 in Chronic Lymphocytic Leukemia nanUNKNOWN
Inflammatory Biomarkers in Seizure nanUNKNOWN
IL-11 in the Development of Multiple Sclerosis nanUNKNOWN
Nivolumab in mRCC Patients: Treg Function, T-cell Access and NK Interactions to Predict and Improve Efficacy nanCOMPLETED
The Role of MMPs in the CXCL12-Induced Invasion of Laryngeal and Hypopharyngeal Squamous Cell Carcinoma nanUNKNOWN
The Role of SDF-1/CXCR4 in Metastasis of Oral Squamous Cell Carcinoma nanUNKNOWN
Lung-Resident Memory Th2 Cells in Asthma nanACTIVE_NOT_RECRUITING
LoViReT (Low Viral Reservoir Treated Patients) nanCOMPLETED
Comparative Study Between Alzheimer's and Multi-infarct Dementia nanUNKNOWN
Evaluation of Macrophage Inflammatory Protein-1α as a Periodontal Disease Biomarker nanCOMPLETED
Biomarkers and Disease Activity in Patients Treated With Teriflunomide (Aubagio) nanCOMPLETED
Fetal Cell Receptors Repertoire nanRECRUITING
Prebiotic Effect of Eicosapentaenoic Acid Treatment for Colorectal Cancer Liver Metastases nanCOMPLETED
Assessment of CXCL5 Level in SLE Patients and Its Correlation with Disease Activity nanNOT_YET_RECRUITING
Measuring the Healthy Pediatric Inflammatory Response to Vaccination. nanENROLLING_BY_INVITATION
Evaluating Urinary CXCL10 for Enhanced Detection of Acute Rejection in Kidney Transplant Patients With Low DD-CFDNA nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a CCRL2 binder may also engage these)

ProteinNameSimilarity
Q9XSD7 — 1.000 Q9XSD7 →
Q0II78 — 1.000 Q0II78 →
Q75ZH0 — 0.996 Q75ZH0 →
P69333 — 0.992 P69333 →
P69332 — 0.992 P69332 →
Q89609 — 0.991 Q89609 →
F5HF62 — 0.990 F5HF62 →
P51676 — 0.990 P51676 →
O35457 — 0.989 O35457 →
P35411 — 0.989 P35411 →
Q0VDU3 — 0.988 Q0VDU3 →
P56412 — 0.987 P56412 →
CCR2 C-C chemokine receptor type 2 0.987 landscape →
P34997 — 0.987 P34997 →
Q9Z0D9 — 0.986 Q9Z0D9 →
O54814 — 0.986 O54814 →
P35351 — 0.986 P35351 →
A6QNL7 — 0.986 A6QNL7 →
Q9BDS8 — 0.986 Q9BDS8 →
Q2Y2P0 — 0.985 Q2Y2P0 →
Q9N0Z0 — 0.985 Q9N0Z0 →
Q2KTE1 — 0.985 Q2KTE1 →
Q9Z0Z6 — 0.985 Q9Z0Z6 →
CX3CR1 CX3C chemokine receptor 1 0.984 landscape →
P51675 — 0.984 P51675 →
O18982 — 0.984 O18982 →
Q9BG77 — 0.984 Q9BG77 →
P46090 — 0.984 P46090 →
Q9TSQ8 — 0.983 Q9TSQ8 →
GPR18 N-arachidonyl glycine receptor 0.983 landscape →