Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11078195 | 0.88 | HRH3 (0.34) | — | |
| SCHEMBL11263936 | 0.86 | TSHR (0.32) | TSHRLMNACYP3A4NFKB1ADRA1A | |
| SCHEMBL11105550 | 0.86 | HRH3 (0.37) | — | |
| SCHEMBL11075879 | 0.86 | — | — | |
| SCHEMBL11097319 | 0.82 | ALDH1A1 (0.42) | — | |
| SCHEMBL11069006 | 0.80 | EPHX1 (0.36) | TSHR | |
| SCHEMBL11076596 | 0.80 | KMT2A (0.45) | — | |
| SCHEMBL11080332 | 0.79 | MME (0.37) | TSHRLMNACYP3A4NFKB1ADRA1A | |
| SCHEMBL11257066 | 0.78 | MEN1 (0.33) | — | |
| SCHEMBL11262679 | 0.78 | CYP2D6 (0.34) | RAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0026369-B1 | CARBAMATES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1984-08-08 | — | — | EP | disclosed |
| US-4335138-A | HYPNOTIC, SEDATIVE | BASF AKTIENGESELLSCHAFT (DE) | 1982-06-15 | — | — | US | disclosed |
| EP-0026369-A2 | Carbamates, their preparation and pharmaceutical compositions containing them | BASF Aktiengesellschaft (DE) | 1981-04-08 | — | — | EP | disclosed |