⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11073951 | 1.00 | — | — | |
| SCHEMBL11071759 | 1.00 | — | — | |
| SCHEMBL10961397 | 1.00 | — | — | |
| SCHEMBL8540818 | 0.88 | — | — | |
| SCHEMBL11072964 | 0.88 | — | — | |
| SCHEMBL11072961 | 0.88 | — | — | |
| SCHEMBL11071392 | 0.88 | — | — | |
| SCHEMBL11071397 | 0.87 | — | — | |
| SCHEMBL7551368 | 0.82 | THRB (0.33) | — | |
| SCHEMBL7551360 | 0.82 | THRB (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4466980-A | Thiaprostaglandin E1 derivatives, process for production thereof, and pharmaceutical use thereof | TEIJIN LIMITED (JP) | 1984-08-21 | — | — | US | disclosed |
| EP-0051284-A1 | Novel thiaprostaglandin E1 derivatives, process for production thereof, and pharmaceuticals containing these compounds | TEIJIN LIMITED (JP) | 1982-05-12 | — | — | EP | disclosed |