Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 10/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.34 |
| ▸ | LSS | P48449 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11066709 | 0.97 | OPRL1 (0.36) | OPRL1SLC6A4SLC6A3SLC6A2OPRM1 | |
| SCHEMBL11072605 | 0.80 | SLC6A4 (0.41) | SLC6A4SLC6A3SLC6A2OPRK1SIGMAR1 | |
| SCHEMBL11075507 | 0.75 | HTR1D (0.39) | SLC6A4SLC6A3SLC6A2UTS2RLSS | |
| SCHEMBL11067219 | 0.75 | HTR1D (0.38) | SLC6A4SLC6A3UTS2R | |
| SCHEMBL11075649 | 0.74 | SLC6A3 (0.50) | OPRL1SLC6A4SLC6A3SLC6A2OPRK1 | |
| SCHEMBL11073938 | 0.74 | GRIN2B (0.37) | OPRL1OPRM1OPRK1OPRD1UTS2R | |
| SCHEMBL11070194 | 0.74 | HTR1D (0.37) | SLC6A4SLC6A3UTS2R | |
| SCHEMBL11076078 | 0.73 | SLC6A4 (0.49) | OPRL1SLC6A4SLC6A3SLC6A2OPRM1 | |
| SCHEMBL11076146 | 0.73 | HTR1D (0.36) | OPRL1OPRM1UTS2R | |
| SCHEMBL11244959 | 0.72 | SLC6A3 (0.47) | OPRL1SLC6A4SLC6A3SLC6A2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | claimed |
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |