Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KISS1R | Q969F8 | 3/20 | 0.37 |
| ▸ | CRAT | P43155 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.34 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28499674 | 1.00 | ALDH1A1 (0.52) | ALDH1A1KISS1RCRATMEN1LMNA | |
| SCHEMBL14294441 | 0.82 | ALDH1A1 (0.52) | ALDH1A1KISS1RCRATMEN1LMNA | |
| SCHEMBL11073459 | 0.82 | ALDH1A1 (0.52) | ALDH1A1KISS1RCRATMEN1LMNA | |
| SCHEMBL18403738 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KISS1RCRATMEN1LMNA | |
| SCHEMBL20662884 | 0.78 | ALDH1A1 (0.48) | ALDH1A1KISS1RPLA2G10 | |
| SCHEMBL7731861 | 0.78 | ALDH1A1 (0.53) | ALDH1A1CRATMEN1LMNAKMT2A | |
| SCHEMBL27905207 | 0.78 | ALDH1A1 (0.48) | ALDH1A1KISS1RCRATMEN1LMNA | |
| SCHEMBL23116550 | 0.77 | ALDH1A1 (0.47) | ALDH1A1KISS1RCRATMEN1LMNA | |
| SCHEMBL20144715 | 0.77 | ALDH1A1 (0.47) | ALDH1A1 | |
| SCHEMBL23116551 | 0.77 | ALDH1A1 (0.47) | ALDH1A1KISS1RCRATMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4439438-A | ANTIDEPRESSANTS, INOTROPIC AGENTS | CAVAZZA CLAUDIO (IT) | 1984-03-27 | — | — | US | claimed |
| US-4439438-A | ANTIDEPRESSANTS, INOTROPIC AGENTS | CAVAZZA CLAUDIO (IT) | 1984-03-27 | — | — | US | disclosed |