SCHEMBL11074016

SCHEMBL11074016

CC/C=C/C(C(O)C(C)(C)Cc1ccc(Cl)cc1)n1cncn1

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.56
KMT2A Q03164 3/20 0.56
POLB P06746 1/20 0.45
HSP90AA1 P07900 1/20 0.45
TDP1 Q9NUW8 2/20 0.42
CYP19A1 P11511 7/20 0.41
CYP3A4 P08684 2/20 0.39
ALDH1A1 P00352 2/20 0.38
MAPT P10636 1/20 0.34
RAB9A P51151 1/20 0.33
ATM Q13315 1/20 0.33
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11074019 1.00 MEN1 (0.56) MEN1KMT2APOLBHSP90AA1TDP1
SCHEMBL9823627 0.81 MEN1 (0.68) MEN1KMT2APOLBHSP90AA1TDP1
SCHEMBL10765937 0.78 MEN1 (0.65) MEN1KMT2APOLBHSP90AA1TDP1
SCHEMBL11075839 0.78 CYP3A4 (0.49) MEN1KMT2APOLBHSP90AA1TDP1
SCHEMBL11075842 0.78 CYP3A4 (0.49) MEN1KMT2APOLBHSP90AA1TDP1
SCHEMBL9390510 0.77 MEN1 (0.63) MEN1KMT2APOLBHSP90AA1TDP1
SCHEMBL36911 0.72 MEN1 (1.00) MEN1KMT2APOLBHSP90AA1TDP1
SCHEMBL22609989 0.72 MEN1 (1.00) MEN1KMT2APOLBHSP90AA1TDP1
SCHEMBL68549 0.72 MEN1 (1.00) MEN1KMT2APOLBHSP90AA1TDP1
SCHEMBL912888 0.72 MEN1 (1.00) MEN1KMT2APOLBHSP90AA1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0100952-A1 Substituted azolylallyl ketones and carbinols BAYER AG (DE) 1984-02-22 EP disclosed