Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9390510 | 0.89 | MEN1 (0.63) | MEN1KMT2ATDP1POLBHSP90AA1 | |
| SCHEMBL10765937 | 0.83 | MEN1 (0.65) | MEN1KMT2ATDP1POLBHSP90AA1 | |
| SCHEMBL10734466 | 0.82 | KMT2A (0.78) | MEN1KMT2ATDP1POLBHSP90AA1 | |
| SCHEMBL912888 | 0.81 | MEN1 (1.00) | MEN1KMT2ATDP1POLBHSP90AA1 | |
| SCHEMBL68549 | 0.81 | MEN1 (1.00) | MEN1KMT2ATDP1POLBHSP90AA1 | |
| SCHEMBL3678556 | 0.81 | MEN1 (1.00) | MEN1KMT2ATDP1POLBHSP90AA1 | |
| SCHEMBL36911 | 0.81 | MEN1 (1.00) | MEN1KMT2ATDP1POLBHSP90AA1 | |
| SCHEMBL8566021 | 0.81 | MEN1 (1.00) | MEN1KMT2ATDP1POLBHSP90AA1 | |
| SCHEMBL22609989 | 0.81 | MEN1 (1.00) | MEN1KMT2ATDP1POLBHSP90AA1 | |
| SCHEMBL11074016 | 0.81 | MEN1 (0.56) | MEN1KMT2ATDP1POLBHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301393-B1 | 1,4-DISUBSTITUTED 1-AZOLYL-3,3-DYMETHYLBUTANE DERIVATIVES | BAYER AG (DE) | 1991-08-14 | — | — | EP | disclosed |
| US-4968712-A | PHYTOPATHOGENS, AGRICULTURE | BAYER AKTIENGESELLSCHAFT (DE) | 1990-11-06 | — | — | US | disclosed |
| EP-0301393-A1 | 1,4-Disubstituted 1-azolyl-3,3-dymethylbutane derivatives | BAYER AG (DE) | 1989-02-01 | — | — | EP | disclosed |