SCHEMBL11074265

SCHEMBL11074265

CC=CC(=O)OCCC[Si](O[Si](C)(C)CCC(=O)O)(O[Si](C)(C)CCC(=O)O)O[Si](C)(C)CCC(=O)O

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.37
HCAR2 Q8TDS4 4/20 0.36
MAPT P10636 1/20 0.30
RAB9A P51151 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10798029 0.91 ATM (0.34) ATMHCAR2
SCHEMBL10793649 0.91 ATM (0.34) ATMHCAR2
SCHEMBL11079928 0.86 ATM (0.37) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL9576346 0.84 ATM (0.38) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL9576292 0.84 ATM (0.38) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL1534165 0.84 TSHR (0.46) ATMHCAR2
SCHEMBL11074235 0.84 TSHR (0.36) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL35808 0.84 ATM (0.44) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL8644260 0.84 ATM (0.44) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL11073255 0.83 ATM (0.37) ATMHCAR2MAPTRAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4463149-A UNSATURATED POLYSILOXANES POLYMER TECHNOLOGY CORPORATION (US) 1984-07-31 US claimed
US-4463149-A UNSATURATED POLYSILOXANES POLYMER TECHNOLOGY CORPORATION (US) 1984-07-31 US disclosed