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SCHEMBL11079928

SCHEMBL11079928

CC=CC(=O)OCCC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](CCCC(=O)O)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ ATM Q13315 1/20 0.37
▸ HCAR2 Q8TDS4 4/20 0.36
▸ EPHX2 P34913 2/20 0.30
▸ ALDH1A1 P00352 1/20 0.30
▸ MAPT P10636 1/20 0.30
▸ RAB9A P51151 1/20 0.30
▸ NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10798029 0.93 ATM (0.34) ATMHCAR2
SCHEMBL10793649 0.93 ATM (0.34) ATMHCAR2
SCHEMBL333003 0.91 ATM (0.43) ATMHCAR2ALDH1A1MAPTRAB9A
SCHEMBL35808 0.90 ATM (0.44) ATMHCAR2ALDH1A1MAPTRAB9A
SCHEMBL8644260 0.90 ATM (0.44) ATMHCAR2ALDH1A1MAPTRAB9A
SCHEMBL11076636 0.86 TSHR (0.36) ATMHCAR2ALDH1A1MAPTRAB9A
SCHEMBL11074265 0.86 ATM (0.37) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL11075201 0.86 ATM (0.39) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL11068067 0.86 ATM (0.39) ATMHCAR2ALDH1A1MAPTRAB9A
SCHEMBL9304052 0.85 ATM (0.43) ATMHCAR2ALDH1A1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4463149-A UNSATURATED POLYSILOXANES POLYMER TECHNOLOGY CORPORATION (US) 1984-07-31 — — US claimed
US-4463149-A UNSATURATED POLYSILOXANES POLYMER TECHNOLOGY CORPORATION (US) 1984-07-31 — — US disclosed