Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 5/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 2/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11069606 | 0.85 | OPRL1 (0.40) | OPRL1DPP4DPP8DPP9CCR3 | |
| SCHEMBL11066053 | 0.82 | OPRL1 (0.49) | OPRL1DPP4DPP8DPP9MCHR1 | |
| SCHEMBL11073882 | 0.79 | OPRL1 (0.52) | OPRL1CCR3KMT2AMEN1CCR1 | |
| SCHEMBL11078536 | 0.79 | OPRL1 (0.42) | OPRL1SLC6A4SLC6A3 | |
| SCHEMBL11074296 | 0.78 | OPRL1 (0.42) | OPRL1DPP4DPP8DPP9KMT2A | |
| SCHEMBL11072870 | 0.78 | OPRL1 (0.42) | OPRL1KMT2ACCR1 | |
| SCHEMBL11081934 | 0.78 | OPRL1 (0.51) | OPRL1SLC6A4SLC6A2KMT2AMEN1 | |
| SCHEMBL11069516 | 0.77 | OPRL1 (0.50) | OPRL1 | |
| SCHEMBL11070148 | 0.76 | OPRL1 (0.49) | OPRL1KMT2AKDM2B | |
| SCHEMBL11070722 | 0.75 | OPRL1 (0.40) | OPRL1KMT2ACCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |