Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 8/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11070722 | 0.91 | OPRL1 (0.40) | OPRL1KMT2ACCR1POLBOPRM1 | |
| SCHEMBL11069208 | 0.89 | OPRL1 (0.38) | OPRL1KMT2ACCR1POLBOPRM1 | |
| SCHEMBL11072870 | 0.86 | OPRL1 (0.42) | OPRL1KMT2ACCR1POLBOPRM1 | |
| SCHEMBL11069872 | 0.86 | SLC18A3 (0.34) | OPRL1KMT2AOPRM1 | |
| SCHEMBL11075757 | 0.86 | OPRL1 (0.43) | OPRL1KMT2ACCR1POLBOPRM1 | |
| SCHEMBL11071160 | 0.85 | SLC6A3 (0.38) | OPRL1KMT2ACCR1POLBOPRM1 | |
| SCHEMBL11077581 | 0.85 | OPRL1 (0.35) | OPRL1KMT2ACCR1POLB | |
| SCHEMBL11069769 | 0.84 | OPRL1 (0.34) | OPRL1KMT2ACCR1POLB | |
| SCHEMBL11078645 | 0.79 | SLC6A3 (0.36) | OPRL1KMT2ACCR1OPRM1 | |
| SCHEMBL11073882 | 0.78 | OPRL1 (0.52) | OPRL1KMT2ACCR1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |